Southeast Ohio Vacation Packages 2026 from $732

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Your Southeast Ohio Vacation

Choose a vacation package to Southeast Ohio and make planning your getaway quick and easy. With the logistics arranged before you depart, you can focus on enjoying every second in this destination. Begin your trip to Southeast Ohio with some time in Clarksville visiting popular sights like KFC Yum Center and Kentucky Kingdom. Athens is another city that lures crowds from far and wide. Fun Barn and Strouds Run State Park are two of the top places to see in this destination. Expedia is a one-stop shop for planning your Southeast Ohio vacation. From accommodations and flights, to car rentals and activities, we know how to create a travel experience like no other.

The Latest Southeast Ohio vacation packages

Price found within the past 48 hours. Click for updated prices.

The Westin Pittsburgh, a Marriott Hotel

Downtown Pittsburgh

$732

per person

Nov 16 - Nov 19

found 1 day ago

Roundtrip flight included

Dallas (DFW) to Pittsburgh (PIT)

8.6/10 Excellent! (1,001 reviews)

Jungle House Designer Residences – Downtown Columbus

Italian Village

Save 100% on your flight

$1,076

per person

Nov 11 - Nov 15

found 18 hours ago

Roundtrip flight included

New York (NYC) to Columbus (CMH)

10/10 Exceptional! (18 reviews)

Stay Pittsburgh

Downtown Pittsburgh

$887

per person

Dec 18 - Dec 21

found 15 hours ago

Roundtrip flight included

Los Angeles (LAX) to Pittsburgh (PIT)

8/10 Very Good! (334 reviews)

Jungle House Luxury Stays - Downtown Columbus & Short North

Downtown Columbus

$917

per person

Nov 11 - Nov 15

found 18 hours ago

Roundtrip flight included

New York (NYC) to Columbus (CMH)

9.6/10 Exceptional! (18 reviews)

Luxury Modern Harrison West Townhome

Downtown Columbus

Save 100% on your flight

$1,153

per person

Nov 11 - Nov 15

found 18 hours ago

Roundtrip flight included

New York (NYC) to Columbus (CMH)

10/10 Exceptional! (1 review)

Great property! We rented both units. Plenty of room for 14 of us. 8 adults and 6 kids from 13 to 1. Very quiet neighborhood,

Reviewed on Jul 30, 2026

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Where to stay in Southeast Ohio

Find the best Southeast Ohio areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Ohio

West Logan

West Logan might not have many top sights, but Logan Antique Mall and Paul A. Johnson Pencil Sharpener Museum are two attractions nearby that you can check out.

Wheeling Island

1 out of top 10 points of interest in this area

If you're spending some time in Wheeling Island, Wheeling Island Casino and Racetrack and Wheeling Suspension Bridge are top sights worth seeing.

Downtown Wheeling

1 out of top 10 points of interest in this area

While visiting Downtown Wheeling, you might make a stop by sights like West Virginia Independence Hall and Capitol Theater.

Downtown Cambridge

If you're spending some time in Downtown Cambridge, Dickens Victorian Village and The National Museum of Cambridge Glass are top sights worth seeing.

Stay near popular Southeast Ohio attractions

A large brick building with multiple windows and a tower, surrounded by trees and a grassy area.

Ohio University

9.6/10 (682 reviews)

Explore the campus of Ohio University, during your travels in Athens. Discover the bars and its entertainment venues while you're in the area.

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A large brick building with a prominent tower and columns.

Denison University

9.2/10 (151 reviews)

Enjoy the collegiate vibe when you visit Denison University, during your trip to Granville. Take in the entertainment venues in this romantic area.

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Mothman Museum

9.4/10 (92 reviews)

You can spend an afternoon browsing the exhibits at Mothman Museum during your travels in Point Pleasant. You can enjoy the bars while in the area.

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Old Man's Cave

9.6/10 (357 reviews)

Explore the great outdoors at Old Man's Cave, a lovely green space in South Bloomingville. You can seek out the hiking trails while in the area.

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Capitol Theater

8.4/10 (79 reviews)

Get tickets for a show at Capitol Theater, a theater with a story to tell in Wheeling. While you're in the area, find time to visit its casinos.

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Hocking Hills Regional Welcome Center

9.4/10 (243 reviews)

Hocking Hills Regional Welcome Center is just one of the places to see in Logan, so why not enjoy the other things to explore during your travels? Amble around the area's parks, or seek out its hiking trails.

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Southeast Ohio Hotel Deals

Days Inn by Wyndham Columbus East Airport

2100 Brice Road Reynoldsburg OH

$74 nightly

$87 total

Nov 9 - Nov 10

Total with taxes and fees

Ohio University Inn & Conference Center

331 Richland Ave Athens OH

Fully refundableReserve now, pay when you stay

$130 nightly

$147 total

Oct 27 - Oct 28

Total with taxes and fees

9.4/10 Exceptional! (1,015 reviews)

"Very cute hotel. Would love to stay in warmer months."

Reviewed on Oct 8, 2026

Christopher Inn and Suites

30 North Plaza Boulevard Chillicothe OH

Fully refundableReserve now, pay when you stay

$155 nightly

$177 total

Oct 12 - Oct 13

Total with taxes and fees

9/10 Wonderful! (1,398 reviews)

"Very clean and nice place to stay. We’d stay there again."

Reviewed on Oct 10, 2026

See all 3,188 properties in Southeast Ohio

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.